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TREATMENTS FOR RETINAL DISORDERS
专利权人:
Enrique Rodriguez-Boulan;Marcelo Nociari
发明人:
Enrique Rodriguez-Boulan,Marcelo Nociari
申请号:
US13980687
公开号:
US20140038918A1
申请日:
2012.01.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy.
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