A vesicle composition comprising the components (A), (B) and (C) mentioned below and has a pH value of 2 to 11: (A) 0.0001- 20 mass% of an organic acid represented by general formula (1) [wherein R1 represents a residue obtained by removing a hydrogen atom from a hydroxy group in natural sterin having one hydroxy group or a hydrogenated product thereof or a bile acid R2 represents a bivalent hydrocarbon group having 1-24 carbon atoms and M represents a hydrogen atom, an alkali metal, an alkali earth metal, ammonium, an alkanolammonium having 2-9 carbon atoms in total, an alkylammonium or an alkenylammonium each having 1-22 carbon atoms in total, a pyridinium residue substituted by an alkyl or alkenyl group having 1-18 carbon atoms, or a basic amino acid] (B) 0.0001-10 mass% of a sphingosine compound and (C) water.
