GODFRIN, Yann,BOURGEAUX, Vanessa,GAY, Fabien,CORTESE, Thomas
申请号：
AU2018201237
公开号：
AU2018201237A1
申请日:
2018.02.21
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018201237A120180315.pdf#####Abstract Pharmaceutical composition comprising erythrocytes encapsulating a PLPdependent enzyme and its cofactor. The invention relates to a pharmaceutical composition containing a PLPdependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine betasynthase.
