JOO, CHUL GUE,주철규,LEE, KEUN HA,이근하,JOO, YEON JEONG,주연정,CHO, YOUNG LONG,조영롱,PARK, CHUNG,박청,KWON, SUN SANG,권순상,JUNG, YONG CHUL,정용철,JOO, IL WOO,주일우
申请号：
KR1020110140245
公开号：
KR1020130072706A
申请日:
2011.12.22
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A cosmetic material and an external use skin composition containing a Paeonia lactiflora extract with high content taxifolin are provided to improve whitening, anti-wrinkling, anti-inflammatory, and antibacterial effects, to treat atopic dermatitis, and protect skin from UV ray. CONSTITUTION: A method for preparing a Paeonia lactiflora extract containing taxifolin comprises the steps of: extracting Paeonia lactiflora with a solvent； drying the extract by reduced pressure and concentrating to obtain primarily concentrated powder； dissolving the primarily concentrated powder in water and adding an organic solvent to fraction according to polarity； removing the solvent and concentrating to obtain a secondarily concentrated powder； dissolving the secondarily concentrated powder in a solution and removing pigments and chlorophyll using a column； crystallizing the extract at ultralow temperature or ultra high pressure； and spray-drying or freeze-drying the recrystallized extract to obtain powdery Paeonia lactiflora extract containing taxifolin-3-glucoside. [Reference numerals] (AA) Extraction step of eluting taxifolin-3-glucoside from Paeonia lactiflora； (BB) Concentration step of drying the eluted extract by reduced pressure； (CC) Fraction step of isolating the concentrated extract by polarity； (DD) Concentration step for removing an organic solvent from the fraction liquid； (EE) Column step for removing pigments and chlorophyll from the concentrated fractioned powder； (FF) Recrystallizing step of precipitating the column liquid using temperature and pressure； (GG) Step of acquiring recrystallized precipitate본 발명은 작약으로부터 탁시폴린 함유 추출물을 제조하는 방법에 관한 것으로, 더욱 자세하게는 작약을 용매 추출하여 탁시폴린 배당체를 함유하는 추출액을 수득하고, 이를 농축, 분획 및 초저온 또는 초고압 재결정을 공정거쳐, 고함량의 탁시폴린을 함유하는 작약추출물을 제조하는 방법 및 상기 방법으로 제조된 탁시폴린 고함유 작약추출물을 유효성분으로 포함하는 미백, 주름개선, 항염, 항균, 아토피 개선 및 자외선 보호효과가 우수한 화장료 및 피부외용제에 관한 것이다. 본 발명에 따르면, 작약으로부터 고함량의 탁시폴린을 함유하는 추출물을 제조할 수 있으며, 상기 추출물을 함유하는 화장료 및 피부외용제 조성물은 미백효과, 주름개선효과, 항염효과,
