PULMAGEN THERAPEUTICS (SYNERGY) LIMITED;ASTRAZENECA AB
发明人:
RHONAN LEE FORD,ANDREW NIGEL MATHER,ANTONIO METE,RICHARD JAMES BULL,ELIZABETH ANNE SKIDMORE
申请号:
BRPI0822693
公开号:
BRPI0822693A2
申请日:
2008.05.13
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention provides named compounds of formula (I), wherein R4 is a N-substituted quinuclidine (I) pharmaceutical compositions containing them and a process for preparing the pharmaceutical compositions. Their use in therapy for the treatment of conditions mediated by M3 muscarinic receptors, such as chronic obstructive pulmonary disease is also disclosed.