Peter H. Seeberger,Claney Lebev Pereira,Guozhi Xiao,Naeem Khan,Chakkumkal Anish
申请号：
US15560719
公开号：
US20180078630A1
申请日:
2016.03.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to synthetic saccharides of general formula (I): V*—[Ux+2—Ux+1—Ux]n—V—O-L-NH2 that are related to carbapenem-resistant Klebsiella pneumoniae capsular polysaccharide and conjugates thereof. Said conjugates and pharmaceutical composition containing said conjugates are useful for prevention and/or treatment of diseases associated with carbapenem-resistant Klebsiella pneumoniae. Furthermore, the synthetic saccharides of general formula (I): V*—[Ux+2—Ux+1—Ux]n—V—O-L-NH2 are useful as marker in immunological assays for detection of antibodies against carbapenem-resistant Klebsiella pneumoniae bacteria.
