PROBLEM TO BE SOLVED: To provide a therapeutic method that increases the medicinal effects of taxane-based antitumor agents on various tumors.SOLUTION: As a result of researches for a method for enhancing the antitumor effects of taxane-based antitumor agents, the inventors have achieved the present invention by confirming that a pharmaceutical composition for the treatment of cancer containing NO production inhibitors as an active ingredient enhances the antitumor effects of taxane-based antitumor agents. Namely, the present invention relates to a pharmaceutical composition for the treatment of cancer, which contains NO production inhibitors as an active ingredient, and which is for administration in combination with one or more antitumor agents selected from among taxane-based antitumor agents.【課題】タキサン系抗腫瘍剤の、各種腫瘍に対する薬効を増大させる治療方法が求められている。【解決手段】本発明者は、タキサン系抗腫瘍剤の抗腫瘍作用増強方法について検討した結果、NO産生抑制剤を有効成分として含有する癌治療用医薬組成物が、タキサン系抗腫瘍剤の抗腫瘍作用を増強させることを確認し、本発明を完成した。即ち、本願は、タキサン系抗腫瘍剤から選択される1以上の抗腫瘍剤との併用投与用であるNO産生抑制剤を有効成分として含有する癌治療用医薬組成物に関する。【選択図】図７
