Pharmaceutical composition for anticancer and cancer metastasis suppression comprising a fusion peptide that simultaneously targets cancer cells and tumor-related macrophages as an active ingredient
The present invention relates to a pharmaceutical composition for anticancer and cancer metastasis suppression comprising a fusion peptide as an active ingredient. More specifically, the present invention relates to cancer cells and tumor-related tumor cells that overexpress IL-4 receptor. The present invention relates to a pharmaceutical composition that exhibits an excellent anticancer effect and cancer metastasis suppressing effect by simultaneously targeting macrophages. The pharmaceutical composition of the present invention simultaneously targets tumor cells and tumor-associated macrophages and kills the cells, thereby simultaneously having an anticancer effect and a cancer metastasis suppressing effect. Furthermore, the fusion peptide of the present invention exhibits an anticancer and cancer metastasis suppressing effect while reducing side effects of the conventional anticancer effect by co-administering with a conventional anticancer drug.本発明は、融合ペプチドを有効成分として含む抗癌及び癌転移抑制用薬学的組成物に関するものであって、より詳細には本発明は、IL-4受容体を過剰発現する癌細胞及び腫瘍関連マクロファージを同時に標的することにより、優れた抗癌効果及び癌転移抑制効果を示す薬学的組成物に関する。本発明の薬学的組成物は、腫瘍細胞及び腫瘍関連マクロファージを同時に標的し、細胞を死滅させ、それによって抗癌効果及び癌転移抑制効果を同時に有している。さらに、本発明の融合ペプチドは、従来の抗癌薬剤と併用投与することで、従来の抗癌効果の副作用を減少させながら、抗癌及び癌転移抑制効果を示す。