Provided is an oral solid extended release dosage form which prevents drug over-releasing and improves drug dissolubility in lower gastrointestinal, by which a main pharmacological effect exhibits assuredly by once-daily or twice-daily oral administration.The solid extended release dosage form comprises (A) pharmacologically active drug, (B) carboxyvinyl polymer, (C) povidone and (D) carmellose sodium, xanthan gum or carboxy methyl starch sodium.本發明提供一種經口投予用徐放性固形製劑,可避免藥物的過量釋出,並藉由改善藥劑於消化道下部的溶出性,能以1日1次或2次的經口投予確實地發揮主藥理效果。其為一種徐放性固形製劑,含有:(A)藥理上有活性的藥物、(B)羧基乙烯基聚合物、(C)聚乙烯吡咯啶酮、及(D)羧甲醚纖維素鈉、黃原膠或羧甲基澱粉鈉。
