MULTI-SPECIFIC ANTIGEN-BINDING MOLECULE HAVING ALTERNATIVE FUNCTION TO FUNCTION OF BLOOD COAGULATION FACTOR VIII

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

IGAWA, TOMOYUKI,SAMPEI, ZENJIRO,KOJIMA, TETSUO,SOEDA, TETSUHIRO,MUTO, ATSUSHI,KITAZAWA, TAKEHISA,NISHIDA, YUKIKO,IMAI, CHIFUMI,SUZUKI, TSUKASA,YOSHIHASHI, KAZUTAKA

申请号：

RSP20180318

公开号：

RS57038B1

申请日:

2011.11.17

申请国别(地区):

RS

年份:

2018

代理人:

摘要：

Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.

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中国工程科技知识中心

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http://www.ckcest.cn/home/