Methods and systems for inducible ablation of neural cells

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专利权人:

The University of Chicago

发明人:

Popko, Brian,Traka, Maria

申请号：

AU2010289419

公开号：

AU2010289419A1

申请日:

2010.09.02

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention relates to methods and systems for inducible ablation of neural cells, in particular non-proliferating cells, such as oligodendrocytes and Schwann cells. The methods and systems include an animal model that can be specifically induced to display phenotypic traits or characteristics of a demyelination condition. The methods and systems disclosed herein are useful for drug screening, by identifying compounds or agents that promote remyelination or reversal of phenotypic traits or characteristics of demyelination conditions.

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中国工程科技知识中心

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http://www.ckcest.cn/home/