INHIBITEUR DE L'EXPRESSION DE FACTEURS FAVORISANT LE CANCER, METHODE DE CRIBLAGE POUR PRINCIPE ACTIF DE CELUI-CI, CASSETTE D'EXPRESSION UTILE DANS LADITE METHODE, MEDICAMENT DE DIAGNOSTIC ET METHODE DE DIAGNOSTIC
NIPPON ZOKI PHARMACEUTICAL CO., LTD.;NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
发明人:
ASAHARA, HIROSHI,CHIBA, TOMOKI,ABE, KENTARO
申请号：
CA3082006
公开号：
CA3082006A1
申请日:
2018.11.09
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The purpose of this invention is to discover a novel factor which affects the level of expression of cancer-promoting factors, to provide an inhibitor of the expression of cancer promoting-factors and development tool therefor, which are based on this novel factor, and to provide a cancer diagnostic drug and a diagnostic method. Provided are: an inhibitor for the expression of cancer-promoting factors, containing at least one inhibitor selected from the group consisting of inhibitors of RBMS expression and inhibitors of RBMS function； a screening method which uses RBMS expression or function as an indicator； an expression cassette useful in said method； a cancer diagnostic drug containing an agent for detecting RBMS gene expression products； and a cancer detection method which takes the level of expression of the RBMS gene as an indicator.
