您的位置: 首页 > 农业专利 > 详情页

Pyrrolidinyl alkyl amide derivatives, their preparation and therapeutic application as CCR3 receptor ligands
专利权人:
SANOFI
发明人:
PAPPNE BEHR, AGNES,BATORI, SÁNDOR,BARTANE BODOR, VERONIKA,SZLAVIK, ZOLTÁN,BATA, IMRE,URBAN SZABO, KATALIN,KAPUI, ZOLTÁN,MIKUS, ENDRE
申请号:
ES09785768
公开号:
ES2483767T3
申请日:
2009.07.29
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
Compounds of the general formula (I) or (IA), wherein Ar1 represents phenyl or naphthyl group-optionally substituted with one or more identical or non-identical, linear or branched C1-4 alkyl groups, linear or branched C1-4 alkoxy group , halogen atom, trifluoromethyl group, cyano group, nitro group, hydroxyl group, C1-2 alkylene dioxy group, amino group, or amino group substituted with one or two identical or non-identical, linear or branched C1-4 alkyl groups; R1 represents hydrogen atom, or C1-4 linear or branched alkyl group; R4, R5, R6a, R6b represents hydrogen atom, or R4 means linear or branched C1-4 alkyl group and R5, R6a and R6b represent hydrogen atom, or R5 means linear or branched C1-4 alkyl group and R4, R6a and R6b represents hydrogen atom, or R6a means linear or branched C1-4 alkyl group and R6b means linear or branched C1-4 alkyl group or hydrogen atom and R5, R4 represents hydrogen atom; Y, Z independently represent linear C1-4 alkylene group - optionally substituted with one or more identical or non-identical, linear or branched C1-4 alkyl groups; Ar2 represents a phenyl, thienyl or furyl group, -substituted optionally with one or more identical or non-identical, linear or branched C1-4 alkyl groups, linear or branched C1-4 alkoxy group, halogen atom, hydroxyl group, cyano group, nitro group, trifluoromethyl group, C1-2 alkylene dioxy group, amino group, or amino group substituted with one or two identical or non-identical, linear or branched C1-4 alkyl groups; or 5- or 6-membered heterocyclic ring containing one, two or three nitrogen atoms, or a nitrogen atom and an oxygen atom, or a nitrogen atom and a sulfur atom - optionally substituted with one or more C1 alkyl groups -4 identical or non-identical, linear or branched, linear or branched C1-4 alkoxy group, hydroxyl group, halogen atom, nitro group, cyano group, trifluoromethyl group, C1-2 dioxy alkylene group, group -NR7R8, -CONR7R8 or -SO2NR7R8 -where R7 and R8 independently mean hydrogen at
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充