RUSSELL K. RANDOLPH,罗素 K 蓝道夫,羅素 K 藍道夫,HAERI ROH-SCHMIDT,海瑞 罗 史基默德,海瑞 羅 史基默德,MARY A MURRAY,玛莉 A 慕瑞,瑪莉 A 慕瑞,AARON W CRAWFORD,亚伦 W 克劳弗,亞倫 W 克勞弗,KEVIN W GELLENBECK,凯文 W 盖伦贝克,凱文 W 蓋倫貝克,DONALD J PUSATERI,唐纳,罗素 K 蓝道夫,羅素 K 藍道夫,海瑞 罗 史基默德,海瑞 羅 史基默德,玛莉 A 慕瑞,瑪莉 A 慕瑞,亚伦 W 克劳弗,亞倫 W 克勞弗,凯文 W 盖伦贝克,凱文 W 蓋倫貝克
申请号:
TW093127616
公开号:
TWI358300B
申请日:
2004.09.13
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and/or inflammatory response, and subsequently treat diseases and/or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.一種調節細胞激素的組合物,用以調節發炎或免疫調節反應。此組合物可包括至少其中一玫瑰實、藍莓、黑莓、接骨木莓、蔓越橘、迷迭香、丁香、甘菊、蕁麻根、朝鮮薊、靈芝、橄欖萃取物、綠茶萃取物、葡萄子萃取物、白藜蘆醇、非洲豆蔻、齒葉乳香萃取物、boswellia forte、依普黃酮、參雙鍵生殖酚、月見草油、INM-176、琉璃苣油、磷蝦油、至少一種葉黃素(例如蝦青素)、生咖啡萃取物及阿魏酸。換句話說,此發明的組合物可包括:玫瑰實及至少其中一黑莓、藍莓、接骨木莓及任意磷蝦油;或玫瑰實、白藜蘆醇及至少其中一非洲豆蔻及蝦青素。根據此組合物的細胞激素調節及細胞激素反應抑制,其可使用於調節免疫調節與/或者發炎反應,並繼之處理與發炎反應有關的疾病與/或者異常症狀,舉例來說如心臟血管症狀、關節炎、骨質疏鬆症及阿茲海默氏症。