Christian Bartels;Glen Dale;Daniel Milligan;Jutta Heim;Patrick Roussel;Peter Schneider;Yaoquan Liu
发明人:
Patrick Roussel,Jutta Heim,Peter Schneider,Christian Bartels,Yaoquan Liu,Glen Dale,Daniel Milligan
申请号:
US13821250
公开号:
US08962842B2
申请日:
2011.09.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Described are a series of 2-pyridone compounds as a potent and selective new class of type II topoisomerase inhibitors with broad-spectrum antimicrobial activity having the general formula (I); where R1, R2, X, and Y are defined herein Such compounds can be used in methods for treating an infection caused by a gram-positive pathogen, a gram-negative pathogen, or a drug-resistant strains thereof.