Sprankle, Kelly G.,Faraoni, Raffaella,Campbell, Brian T.,Abraham, Sunny,Holladay, Mark W.,Rowbottom, Martin W.,Chao, Qi,Bhagwat, Shripad S.,Lai, Andiliy G.,Setti, Eduardo
申请号:
AU2009226136
公开号:
AU2009226136B2
申请日:
2009.03.17
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Compounds according to formula (I), compositions and methods are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases. Formula (I): or a pharmaceutically acceptable salt, solvate, clathrate of hydrate thereof, wherein X is O or S(O)