R.O.C;Institute of Nuclear Energy Research Atomic Energy Council Executive Yuan
发明人:
申请号:
EP16178202.4
公开号:
EP3184123A1
申请日:
2016.07.06
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The invention discloses a high-yield method for preparing a ribonucleic acid (RNA)-diethyltriamine pentaacetic acid (DTPA) conjugate. The conjugate is prepared by conjugating a RNA or locked nucleic acid (LNA) having an amino group to p-isothiocyanate benzyl-DTPA (SCN-Bn-DTPA) or DTPA anhydride with heating under microwave.