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DÉRIVÉ INDOLECARBOXAMIDE
专利权人:
ASTELLAS PHARMA INC.
发明人:
KANAYAMA, TAKATOSHI,KUBOTA, HIDEKI,MATSUMOTO, SHUNICHIRO,SAITO, TOMOYUKI,SHIMIZU, TAKAFUMI,KATOH, NAOTO,MATSUI, SHIGEO
申请号:
EP13816547
公开号:
EP2873660A4
申请日:
2013.07.09
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
[Problem] To provided a compound which is useful as an MT1 and/or MT2 receptor agonist. [Means for Solution] The present inventors have conducted studies on MT1 and/or MT2 receptor agonists, and have found that an indole carboxamide compound has an MT1 and/or MT2 receptor agonistic action, thereby completing the present invention. The indole carboxamide compound of the present invention has the MT1 and/or MT2 receptor agonistic action as well as a low CNS penetration, and therefore, it can be used as an agent for preventing and/or treating urological diseases; in one embodiment, lower urinary tract symptoms; in another embodiment, urine storage symptom, in another embodiment, urinary incontinence; in a still another embodiment, stress urinary incontinence; and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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