combinations comprising positive allosteric modulators or orthosteric agonists of the subtype 2 metabotropic glutamatergic receptor and their uses

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

ANDRÉS AVELINO TRABANCO-SUAREZ,BRIAN D KLEIN,H STEVEN WHITE,HILDE LAVREYSEN,JOSÉ MARIA CID-NUNEZ,MARC ANDRÉ CEUSTERS,NANCY EULALIE SYLVAIN VAN OSSELAER,ROGER FRANCIS BONE,ROY E TWYMAN,STEFAN MARIA CHR

申请号：

BR112016016390

公开号：

BR112016016390A2

申请日:

2015.01.20

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The present invention relates to combinations comprising a positive allosteric modulator ("PAM") of metabotropic glutamatergic receptor subtype 2 ("mGluR2") or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic receptor subtype 2 compound or a pharmaceutically acceptable salt or a solvate thereof, and a synaptic vesicle protein 2A ("SV2A") ligand.

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中国工程科技知识中心

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http://www.ckcest.cn/home/