The present invention relates to combinations comprising timolol and a compound useful for the treatment of rosacea selected from ivermectin, metronidazole and praziquantel and to the use of these combinations in the topical treatment of rosacea.本發明關於包含噻嗎洛爾以及選自伊維菌素、甲硝唑和吡喹酮的用於治療紅斑痤瘡的化合物的結合物、以及這些結合物在局部治療紅斑痤瘡中的用途。