The present invention is related to a method and a system for detecting signals of pulse diagnosis, and a detecting device of pulse diagnosis. The method comprises following steps. Apply a pressure on an artery of an object, and then detect a pulsation generated from a feedback of the artery at each different pressure value. Compare the similarity of a preset period and a preset vibration amplitude of the artery with a default sphygmogram model at each different pressure value to determine a pressure value of pulse diagnosis by a graphical analog method, and obtain a corresponding sphygmogram according to the pressure value of pulse diagnosis. It will provide standardization and increase the data applicability for personal pulse wave analysis by comparing personal different sphygmogram to determine different pressure value of pulse diagnosis.