A tissue sample receptacle includes a fulcrum body. The fulcrum body is positioned to allow a tissue sample collector to be broken off within the tissue sample receptacle. The fulcrum body provides a fulcrum against which the tissue sample collector may be bent. The fulcrum body may be coupled to the sidewall of the tissue sample receptacle. The fulcrum body may be removable from, may be permanently coupled to, or may be formed integrally with the sidewall.