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NOVEL 2-HETEROARYL SUBSTITUTED BENZOTHIOPHENES AND BENZOFURANES
专利权人:
ASTRAZENECA AB
发明人:
SWAHN, BRITT-MARIE,WENSBO, DAVID,ARZEL, ERWAN
申请号:
NZ57915708
公开号:
NZ579157A
申请日:
2008.03.05
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are 2-heteroaryl substituted benzothiophene and benzofurane compounds of formula (Ia), wherein the substituents are as described within the specification. Further disclosed is a pharmaceutical composition comprising a compound of formula (Ia), the use of a compound of formula (Ia) in a process for the preparation of a labelled compound, and the use of a compound of formula (Ia) in the manufacture of a medicament for use in in vivo metod for measuring amyloid deposits in a subject, wherein the subject is suspected of having a disease or syndrome selected form Alzheimer's disease, familial Alzheimer's disease, Down's Syndrome and homozygotes for the apolipoprotein E4 allele.
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