The present invention provides a method for preparing hydrophilic polymer foam. The method comprises a step of providing an isocyanate functionalized prepolymer (A) and a step of foaming and curing the prepolymer (A). The prepolymer (A) is prepared by reacting diisocyanate (A1) and polyether polyol (A2), wherein the diisocyanate (A1) is selected from any one and a combination of 1,4-butyl diisocyanate (BDI), lysine diisocyanate (LDI) and 1,5-pentyl diisocyanate (PDI); the polyether polyol (A2) is a copolymer of ethylene oxide (EO) and propylene oxide (PO) and/or butylene oxide (BO); the ethylene oxide has a weight percentage of about 50%-100% in the polyether polyol, and has an OH functionality degree of 3-6, a hydroxyl value of about 21 mg KOH/g-168 mg KOH/g and a number-average molecular weight of about 1000 g/mol to about 8000 g/mol; and NCO content in the prepolymer (A) is 1%-10%.