您的位置: 首页 > 农业专利 > 详情页

תרכובות אוליגופפטידיות ושימושים בהן
专利权人:
APIM THERAPEUTICS AS
发明人:
申请号:
IL20738410
公开号:
IL207384A
申请日:
2010.08.03
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
The present invention provides an oligopeptidic compound comprising a PCNA interacting motif, or a nucleic acid molecule comprising a sequence encoding said oligopeptidic compound, for use in treatment of a hyperproliferative disorder, wherein the PCNA interacting motif is [R/K]-[W/F/Y]-[L/I/V/A/M]-[V/L/I/A/M]-[K/R] (SEQ ID NO. 28), wherein the oligopeptidic compound has less than 70 subunits and comprises a cell penetrating peptide comprising an oligomer of 5 to 20 basic amino acids. In certain aspects the compounds of the invention may be used as cytostatic agents in their own right. In other aspects of the invention oligopeptidic compounds comprising such a motif may be used in conjunction with cytostatic agents or with radiotherapy.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充