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cyclopropanamine compounds
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
TOMITA, NAOKI,KAJII, SHIGEO,CARY, DOUGLAS ROBERT,TOMITA, DAISUK,IMAMURA, SHINICHI,TSUCHIDA, KEN,MATSUDA, SATORU,HARA, RYUJIRO
申请号:
MA36798
公开号:
MA35423B1
申请日:
2014.03.05
申请国别(地区):
MA
年份:
2014
代理人:
摘要:
The present invention provides a compound having a lysine-specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for cancer, and central nervous system diseases, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group or heterocyclic group optionally having substituent(s); R is H, a hydrocarbon group or heterocyclic group optionally having substituent(s); A and R are optionally bonded to each other to form a ring optionally having substituent(s); Q 1 , Q 2 , Q 3 and Q 4 are each a hydrogen atom or a substituent; Q 1 and Q 2 , and Q 3 and Q 4 , are each optionally bonded to each other to form a ring optionally having substituent(s); X is H, an acyclic hydrocarbon group or saturated cyclic group optionally having substituent(s); Y 1 , Y 2 and Y 3 are each H, a hydrocarbon group or heterocyclic group optionally having substituent(s); X and Y 1 , and Y 1 and Y 2 , are each optionally bonded to each other to form a ring optionally having substituent(s); and Z 1 , Z 2 and Z 3 are each H or a substituent, or a salt thereof.
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