Monoclonal antibody SC104 and derivative thereof specifically binding to a sialyltetraosyl carbohydrate as a potential anti-tumor therapeutic agent

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专利权人:

CEPHALON AUSTRALIA PTY LTD

发明人:

DURRANT, LINDA GILLIAN,PARSONS, TINA

申请号：

NZ58921405

公开号：

NZ589214A

申请日:

2005.05.11

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Provided is an antibody or fragment thereof comprising a V L domain wherein the V L domain comprises three CDRs wherein the sequence of CDRI is a specified amino acids sequence or a sequence at least 70% identical thereto, and the sequence of CDR3 is a specified amino acid sequence or a sequence at least 70% identical thereto and wherein the antibody or fragment thereof binds Colo205 cells. The antibody can be used to treat tumours.

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