RUAH, SARA S. HADIDA,GROOTENHUIS, PETER D.J.,VAN GOOR, FREDRICK,ZHOU, JINGLAN,BEAR, BRIAN,MILLER, MARK T.,MCCARTNEY, JASON,NUMA, MEHDI MICHEL JAMEL,YANG, XIAOQING
申请号:
PL07755298
公开号:
PL2007756T3
申请日:
2007.04.09
申请国别(地区):
PL
年份:
2016
代理人:
摘要:
Compounds of formula Ic: or a pharmaceutically acceptable salt thereof, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to the use of the compounds of the present invention for the preparation of a medicament for treating ABC transporter mediated diseases, like cystic fibrosis.