FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE ROSSIJSKIJ NAUCHNYJ TSENTR KHIRURGII IM. AKADEMIKA B.V. PETROVSKOGO ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK
发明人:
MIKHAJLOV JURIJ NIKOLAEVICH,Михайлов Юрий Николаевич,SVIRSHCHEVSKIJ EVGENIJ BRONISLAVOVICH,Свирщевский Евгений Брониславович,ADRIANOV SERGEJ OLEGOVICH,Адрианов Сергей Олегович,RODIONOVA TATJANA VIKTOR
申请号：
RU2013137372/14
公开号：
RU0002532524C1
申请日:
2013.08.09
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to functional diagnostics, and can be used in assessing the blood microcirculation status in a patients limbs by determining a relation between the blood flows in the paired organs or paired regions of interest by radionuclide diagnostics. That is ensured by inserting a microcatheter with a two-way cock and two syringes attached, into the ulnar or other forearm vein. One syringe contains an indicator, an amount of which shall not exceed 0.3-0.5 ml, while the other syringe contains normal saline. Immediately after the indicator is introduced into the catheter, it is pushed on by normal saline from the second syringe. A camera is used to record gamma emission and a radioactivity-time curve is constructed. The radioactivity-time curves are rated by an area of the specified regions of interest y1(t)/S1, y2(t)/S2 to construct the initial radioactivity-time curves y1(t), y2(t), which are approximated by orthogonal polynominals α1(t), α2(t) in the form of a parametric curve ψ[α1(t), α2(t)], whereon a straight-line segment is specified between the points t1 and t2 for the following approximation implemented by the least square method and represented by the straight line y=kx+b. Herewith, y is an approximated radioactivity in the 1st region of interest , x is an approximated radioactivity in the 2nd region of interest, k=tgα, wherein α is an inclination of the straight line to an absciss, b is a segment of the y axis from the coordinate origin to a crossing point of the straight line and the y axis. The required relation D is defined as wherein Q1 is the blood flow (ml/min) in the 1st region of interest, Q2 is the blood flow (ml/min) in the 2nd region of interest.EFFECT: method provides the timely and accurate diagnosis of limb pathology by determining the blood flow in the region of interest with respect to the examined limb in relation to this value in the contralateral limb.2 cl, 5 dwg, 1 exИзобретение относ
