PROBLEM TO BE SOLVED: To provide agents effective in the prevention and/or treatment of upper respiratory tract infections including common cold, and of symptoms thereof.SOLUTION: The invention relates to a combination pharmaceutical composition containing a) an activated-potentiated form of an antibody to bradykinin, b) an activated-potentiated form of an antibody to histamine, and c) an activated-potentiated form of an antibody to morphine, as well as to a method for treating and preventing upper respiratory tract conditions or disorders and the symptoms associated therewith by administration of the combination composition.SELECTED DRAWING: Figure 1【課題】普通感冒を含む上気道感染症及びその症状の予防及び/又は治療に有効な剤の提供。【解決手段】a)ブラジキニンに対する活性化増強型抗体と、b)ヒスタミンに対する活性化増強型抗体と、c)モルヒネに対する活性化増強型抗体とを含む組み合わせ医薬組成物、並びに前記組み合わせ組成物を投与することによって上気道の状態又は障害及びそれに関連する症状を治療及び予防するための方法。【選択図】図1