System of the present invention, which provides, to be intended to inhibit the object of heat-resist acid bacterium proliferation using what, it is the antiblastic of the inhibited proliferation of the superior heat-resist acid bacterium of display, and the Proliferation Ability method of the bacterium, the proliferation of heat-resist acid bacterium can be effectively suppressed, and flavor and the good acidic beverages and its manufacturing method of appearance are provided. The lactic acid for the effective quantity that the heat-resist acid bacterium proliferation of inhibition is contained in the antiblastic system of the present invention is effective component, and the Proliferation Ability method of the present invention and manufacturer's genealogy of law of acidic beverages utilize the antiblastic.本發明係提供使用於欲抑制耐熱性好酸性菌增殖之對象物,其為顯示優越的耐熱性好酸性菌之增殖抑制作用之增殖抑制劑,及該菌之增殖抑制方法,可有效抑制耐熱性好酸性菌之增殖,且提供風味及外觀均良好之酸性飲料以及其製造方法。本發明之增殖抑制劑係含有抑制耐熱性好酸性菌增殖之有效量之乳酸為有效成分,本發明之增殖抑制方法及酸性飲料之製造方法係利用該增殖抑制劑。