The present disclosure is directed to individual peptide immunogen constructs targeting portions of the Tau protein for the treatment and/or prevention of tauopathies. The present disclosure is also directed to compositions containing the peptide immunogen constructs, methods of making and using the peptide immunogen constructs, and antibodies produced by the peptide immunogen constructs.本揭露是關於用以治療及/或預防Tau蛋白病之針對Tau蛋白質部分的個別胜肽免疫原結構。本揭露還涉及含有胜肽免疫原結構的組成物,製備和使用胜肽免疫原結構的方法,以及由胜肽免疫原結構產生的抗體。