Mayo Foundation for Medical Education and Research
发明人:
Purna C. Kashyap,Eric J. Battaglioli,Vanessa L. Hale
申请号:
US15762203
公开号:
US20190216861A1
申请日:
2016.09.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
This document relates to biomarkers of gut microbiota dysbiosis. Bacteria that are increased or decreased in gut microbiota dysbiosis can be used as biomarkers to predict dysbiosis in patients with diarrhea and/or to predict susceptibility to Clostridium difficile infection (CDI). In addition, provided herein are compositions including at least three bacteria that are de creased in gut microbiota dysbiosis which can be used, for example, to restore heathy gut microbiota (e.g., by probiotic or by fecal microbiota transplant) to treat CDI.