A valve prosthesis, implantation device,and methods for use are provided. The implantationdevice utilizes moveable ciaspers for both positioningand anchoring the valve prosthesis Alternativedesigns of the devices allow different methods forminimally invasive implantation of a sutureless valveprosthesis, including transapical and transcatheterapproaches Also provided is a delivery device for deliveryof a medical prostheses though minimally invasivemeans. The valve prosthesis is comprised of a supportframe (892) with attached leaflets and a valve clasper(880) that can be attached to the support frame to fixthe prostestis in the pockets of the coronary sinus.