Vadrevu, Krishna Mohan,Ella, Krishna Murthy,Gutla, Victor Jerusha Augustus Harshavardhan,Singhania, Smita
申请号:
AU2007251122
公开号:
AU2007251122B2
申请日:
2007.05.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to a composition comprising a viral antigen, a first protein and a second protein. Optionally, the composition also comprises three different disaccharaides, or, optionally, the composition comprises a primary sugar and at least one, preferably two secondary sugars. The present invention also relates to the use of a viral antigen, a first protein and a second protein for the manufacture of a composition, preferably a vaccine. The present invention furthermore relates to a method of treatment or prevention of virus associates diseases in humans. Moreover, the present invention relates to a method of adapting a virus to a suitable cell-line. The invention is also useful for the production of virus suspensions suitable for making stable, live/inactivated, monovalent and/or polyvalent, liquid/lyophilized rotavirus vaccine compositions for oral and/or nasal or any other suitable route of administration in human.