Raising the barrier function of the oil stratum which forms tears layer, eye obstacle of the dry eye and the like control or it designates that the composition for ophthalmology which it can improve is offered as solution topic of long-cherished desire. In addition, showing obtaining anti- inflammation action and anti-bacterial action, profitably control or it designates cornea & conjunctiva obstacle such as the angular conjunctivitis as solution topic of long-cherished desire that the composition for ophthalmology which it can improve is offered. In long-cherished desire, aporipotanpaku A 1 as a active ingredient, content it tried to obtain in the composition for ophthalmology.涙液層を構成する油層のバリア機能を高めて、ドライアイ等の眼障害を抑制乃至は改善し得る眼科用組成物を提供することを本願の解決課題とする。また、抗炎症作用や抗菌作用を発揮せしめて、角結膜炎等の角膜・結膜障害を有利に抑制乃至は改善し得る眼科用組成物を提供することも本願の解決課題とする。本願において、アポリポタンパクA-1を有効成分として、眼科用組成物に含有せしめるようにした。