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IMMUNOGENIC COMPOSITION
专利权人:
发明人:
CASTADO CINDY,DEVOS NATHALIE ISABELLE,POOLMAN JAN,WEYNANTS VINCENT
申请号:
IN2389/KOLNP/2012
公开号:
IN2012KN02389A
申请日:
2012.08.27
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present disclosure relates to the field of Neisserial immunogenic compositions and vaccines, their manufacture and the use of such compositions in medicine. In particular the present invention relates to compositions and methods involving the factor H binding protein (fHbp) antigen. The present inventors have recognised that fHbp is poorly expressed in neisserial strains of L2 immunotype (and ST11 clonal complex), and vaccines comprising fHbp may be made more effective against said strains by formulating the vaccine with a further antigen that can elicit protection against these strains.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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