Brian A. Johns,Takashi Kawasuji,Teruhiko Taishi,Yoshiyuki Taoda
申请号：
US13763174
公开号：
US08778943B2
申请日:
2013.02.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention is directed to a class of substituted 10-hydroxy-9,11-dioxo-2,3,4a,5,9,11,13,13a-octahydro-1H-pyrido[1,2-a]pyrrolo[1′,2′:3,4]imidazo[1,2-d]pyrazine-8-carboxamides useful as anti-HIV agents. The compounds have the formula (I-1-1):wherein ring A is an optionally substituted hexahydro-1H-pyrrolo[1,2-c]-imidazole； R14 and RX are independently hydrogen or optionally substituted lower alkyl； R3 is selected from various groups； R1 is hydrogen or lower alkyl； R is halogen； m is 0, 1, 2 or 3； or a pharmaceutically acceptable salt thereof.
