Leticia M. Preza;Miroslav Rapta;Sean M. Dalziel;Pierre-Jean Colson
发明人:
Sean M. Dalziel,Leticia M. Preza,Miroslav Rapta,Pierre-Jean Colson
申请号:
US14333003
公开号:
US09290491B2
申请日:
2014.07.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms.