The present disclosure provides closure devices for closing an opening in a body lumen, systems for closing an opening in a body lumen, and methods of making a closure device for closing an opening in a body lumen. The closure device may include a plug, an anchor, a cinch button, and a suture coupled to the anchor, the suture having a plurality of elongate filaments with a predefined cutting segment for cutting the suture, where the plurality of elongate filaments of the predefined cutting segment are bonded together to prevent their relative motion.