Roderick Peter Hafner,Paul Laidler,Pascal Hickey,Mark Larche
申请号：
US14403462
公开号：
US09850281B2
申请日:
2013.05.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Polypeptides which may be used for preventing or treating allergy to moulds of the Cladosporium and/or Alternaria genus, have up to 30 amino acids in length and comprise: (I) the amino acid sequence: (a) GGYKAAVRPTMLE (SEQ ID NO: 35； Cla35), (b) AE V YQKLK SLTKK (SEQ ID NO: 31； Cla16), (c) VAITYASRAQGAE (SEQ ID NO: 32； Cla25), (d) GHHFKERGT-GSLVIT (SEQ ID NO: 33； Cla26), or (e) ANYTQTKTVSIRL (SEQ ID NO: 34； Cla29)； or (II) a T cell epitope-containing variant sequence which is a said amino acid sequence (I) having up to six amino acid modifications, each of which is independently a deletion, substitution or insertion.
