GUILLEMONT, JEROME EMILE GEORGES,MORDANT, CELINE ISABELLE,SCHMITT, BENOIT ANTOINE
申请号：
CA2923637
公开号：
CA2923637C
申请日:
2007.12.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
This invention concerns 5,6-substituted pyrimidine derivatives of formula (see formula I) having HIV (Human Immunodeficiency Virus) replication inhibiting properties and especially having an improved ability to inhibit the replication of mutant strains, in particular of strains that have become resistant to one or more known NNRTI drugs, which strains are referred to as drug-or multidrug-resistant HIV strains. The invention also concerns the preparation of the 5,6-substituted pyrimidine compounds and pharmaceutical compositions comprising these compounds.
