The United States of America, as represented by the Secretary, Dept. of Health and Human Service;Aleta Biotherapeutics, Inc.
发明人:
Roy Lobb,Paul David Rennert,John Todd Schiller
申请号:
US15772134
公开号:
US20180311269A1
申请日:
2016.10.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Some embodiments of the present disclosure are directed to methods that include delivering to a subject a nucleic acid encoding an antigen, wherein the nucleic acid is delivered via a tumor-selective vehicle or via intratumoral injection, and delivering to the subject an immune cell expressing a receptor that binds to the antigen.