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18f-tagged inhibitors of prostate specific membrane antigen (psma) and their use as imaging agents for prostate cancer
专利权人:
DEUTSCHES KREBSFORSCHUNGSZENTRUM;RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG
发明人:
Eder, Matthias,Schäfer, Martin,Haberkorn, Uwe,Eisenhut, Michael,Cardinale, Jens,Kopka, Klaus,Bauder-Wuest, Ulrike,Benesova, Martina,Giesel, Frederik
申请号:
NZ73977016
公开号:
NZ739770A
申请日:
2016.09.19
申请国别(地区):
NZ
年份:
2019
代理人:
摘要:
The present invention relates generally to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer. More particularly, the present invention discloses compounds comprising PMSA-targeting moiety, lipophilic and hydrophobic linkers, and an 18F tag, pharmaceutical compositions comprising same and uses therefor. The compounds of the present invention may have improved efficacy as tracers and imaging agents for various disease states of prostate cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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