THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;NOVARTIS AG
发明人:
BROGDON, JENNIFER,JUNE, CARL H.,LOEW, ANDREAS,MAUS, MARCELA,SCHOLLER, JOHN
申请号：
SG11201506603P
公开号：
SG11201506603PA
申请日:
2014.03.15
申请国别(地区):
SG
年份:
2015
代理人:
摘要：
The invention provides compositions and methods for treating diseases associated with expression of CD19. The invention also relates to chimeric antigen receptor (CAR) specific to CD19, vectors encoding the same, and recombinant T cells comprising the CD19 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD19 binding domain.
