Paul A. Haefner;Yi Zhang;Imad Libbus;Aaron R. McCabe
发明人:
Imad Libbus,Paul A. Haefner,Aaron R. McCabe,Yi Zhang
申请号:
US12469012
公开号:
US08452398B2
申请日:
2009.05.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A neural stimulator senses a reference signal indicative of cardiac cycles each including a predetermined type timing reference event using a sensor external to the heart and blood vessels. The delivery of the neural stimulation pulses are synchronized to that timing reference event. Examples of the timing reference event include a predetermined cardiac event such as a P-wave or an R-wave detected from a subcutaneous ECG signal, a predetermined type heart sound detected from an acoustic signal, and a peak detected from a hemodynamic signal related to blood flow or pressure.