PROBLEM TO BE SOLVED: To provide pharmaceutical compositions and methods of using the compositions for increasing serum, plasma and/or red blood cell (RBC) EPA levels and/or for treating and/or preventing cardiovascular-related disease.SOLUTION: A pharmaceutical composition contains eicosapentaenoic acid or a derivative thereof.SELECTED DRAWING: Figure 1【課題】血漿、血清及び/又は赤血球(RBC)のEPAレベルを増加させるための、並びに/或いは心血管関連疾患を処置又は予防するための、医薬組成物及びかかる組成物の使用方法の提供。【解決手段】エイコサペンタエン酸又はその誘導体を含む医薬組成物。【選択図】図1