Methods for co-encapsulation of combination drugs and co-encapsulated combination drug product

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专利权人:

Trevor Percival Castor

发明人:

Trevor Percival Castor

申请号：

US12384007

公开号：

US08637074B2

申请日:

2009.03.31

申请国别(地区):

US

年份:

2014

代理人:

摘要：

This invention is for an improved process to co-encapsulate hydrophobic drugs and hydrophilic drugs in phospholipid liposomes. Non-toxic supercritical or near-critical fluids with/without polar cosolvents are utilized to solubilize phospholipid materials and hydrophobic drugs, and form uniform liposomes to encapsulate hydrophobic drugs and hydrophilic drugs.

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