Lihua Yu,Kian Huat Lim,Jacob D. Feala,Silvia Buonamici,Yoshiharu Mizui,Peter G. Smith,Ping Zhu,Eunice Sun Park,Michael W. Seiler,Marco Peter Fekkes
申请号:
US15755225
公开号:
US20180318312A1
申请日:
2016.08.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Splice variants associated with neomorphic SF3B1 mutations are described herein. This application also relates to methods of detecting the described splice variants, and uses for diagnosing cancer, evaluating modulators of SF3B1, and methods of treating cancer associated with mutations in SF3B1.