#$%^&*AU2019204443A120190711.pdf#####ABSTRACT Some aspects of the invention provide for a method of treating a patient having glaucoma, a non-hereditary optic neuropathy, steroid-induced oxidative stress, or steroid-induced 5 oxidation-related disorders, comprising identifying a patient having a non-hereditary optic neuropathy or steroid-induced oxidative stress or steroid-induced oxidation-related disorders and in need of treatment; repeatedly administering a polyunsaturated substance to the patient or the patient's tissue, wherein the polyunsaturated substance is chemically modified such that one or more bonds is stabilized against oxidation; wherein following said administration, the 10 polyunsaturated substance or a polyunsaturated metabolite thereof comprising said one or more chemical modifications is incorporated into the patient's body or the patient's tissue.